Clinical Trials

Clinical trials often involve a research study conducted to evaluate a medical procedure or medical product, such as a drug. Not all University of Arizona studies involve drugs or interventions. Some studies use surveys or evaluate medical records to find new and better ways to help people. Others recruit healthy subjects, or controls, to better evaluate and compare results with those of non-healthy subjects.

How to Participate

Whether you’re a potential candidate to participate as a patient or subject in the study, you would like to participate as a "healthy volunteer" for the control group or you’re a research or clinical professional interested in collaborating with the research team—simply contact the study coordinator listed for each individual clinical research study above.

To contact the Division of Nephrology directly, call (520) 626-6371.

FIDELIO-DKD (16244): A randomized, double-blind, placebo-controlled, parallel-group, multicenter, event-driven Phase III study to investigate the efficacy and safety of finerenone, in addition to standard of care, on the progression of kidney disease in subjects with type 2 diabetes mellitus and the clinical diagnosis of diabetic kidney disease. https://clinicaltrials.gov/ct2/show/NCT02540993

FIGARO-DKD (17530): A randomized, double-blind, placebo-controlled, parallel-group, multicenter, event-driven Phase III study to investigate the efficacy and safety of finerenone on the reduction of cardiovascular morbidity and mortality in subjects with type 2 diabetes mellitus and the clinical diagnosis of diabetic kidney disease in addition to standard of care. https://clinicaltrials.gov/ct2/show/NCT02545049

PRO2TECT-CORRECTION (AKB-6548-CI-0014): Phase III, randomized, open-label, active-controlled study evaluating the efficacy and safety of oral vadadustat for the correction of anemia in subjects with non-dialysis-dependent chronic kidney disease (NDD-CKD). https://clinicaltrials.gov/ct2/show/NCT02648347

PRO2TECT-CONVERSION (AKB-6548-CI-0015): Phase III, randomized, open-label, active-controlled study evaluating the efficacy and safety of oral vadadustat for the maintenance treatment of anemia in subjects with non-dialysis-dependent chronic kidney disease (NDD-CKD). https://clinicaltrials.gov/ct2/show/NCT02680574

PRT-201-320: Multicenter, double-blind, placebo-controlled study of vonapanitase (PRT-201) administered immediately after radiocephalic arteriovenous fistula creation in patients with chronic kidney disease. https://clinicaltrials.gov/ct2/show/NCT02414841

LOCK-IT-100: A phase 3, prospective, multicenter, double-blind, randomized, active control study to demonstrate the safety and effectiveness of Neutrolin in preventing catheter-related bloodstream infections in subjects receiving hemodialysis therapy as treatment for end stage renal disease. https://clinicaltrials.gov/ct2/show/NCT02651428

The Access Trial (VT-304): A phase 3, randomized, multicenter, single-blind controlled study evaluating arteriovenous fistula outcomes with and without a perivascular sirolimus-eluting collagen implant in subjects on hemodialysis. https://clinicaltrials.gov/ct2/show/NCT02513303

US OI 124: The PROTECT Study: A prospective observational trial to evaluate the correlation of T-SPOT response to CMV infection and T cell-mediated acute graft rejection. https://clinicaltrials.gov/ct2/show/NCT02382211

1407-004: Clinical evaluation of use of prismocitrate 18 in patients undergoing acute continuous renal replacement therapy (CRRT). https://clinicaltrials.gov/ct2/show/NCT02860130

ZS-005: A phase 3 multicenter, multi-dose, open-label maintenance study to investigate the long-term safety and efficacy of ZS (sodium zirconium cyclosilicate), an oral sorbent, in subjects with hyperkalemia. https://clinicaltrials.gov/ct2/show/NCT02163499