Karen Herbst, MD, PhD

  • Associate Professor, Medicine - (Clinical Scholar Track)
  • Associate Professor, Radiology
  • Associate Professor, Surgery
  • Clinical Associate Professor, Pharmacy Practice-Science
Research Interests: 

Clinical research strives to improve our understanding of the underlying pathophysiology of, and treatment options for, ATDs which includes a focus on the lymphatic system as well as natural supplements.  Her basic science research currently aims to find gene mutations in families with Dercum’s disease.

  • MD: Rush Medical College of Rush University, 1996
  • University of Washington School of Medicine, 2000
  • University of Washington School of Medicine, Endocrinology, 2002
Board Certifications
  • American Board of Internal Medicine
  • American Board of Internal Medicine, Endocrinology, Diabetes & Metabolism Sub-specialty

Select Publications


Ghazala, S., J. Bilal, E. Ross, I. Bin Riaz, B. Kalb, and K. L. Herbst, "Low-Dose d-Amphetamine Induced Regression of Liver Fat Deposits in Dercum Disease.", Am J Med, vol. 131, issue 6, pp. 705-708, 2018 Jun. PMID: 29355511
De la Torre, Y. Sanchez-, R. Wadeea, V. Rosas, and K. L. Herbst, "Lipedema: friend and foe.", Horm Mol Biol Clin Investig, vol. 33, issue 1, 2018 Mar 09. PMCID: PMC5935449  PMID: 29522416


Herbst, K. L., C. Ussery, and A. Eekema, "Pilot study: whole body manual subcutaneous adipose tissue (SAT) therapy improved pain and SAT structure in women with lipedema.", Horm Mol Biol Clin Investig, vol. 33, issue 2, 2017 Sep 20. PMID: 28930626


Buck, D. W., and K. L. Herbst, "Lipedema: A Relatively Common Disease with Extremely Common Misconceptions.", Plast Reconstr Surg Glob Open, vol. 4, issue 9, pp. e1043, 2016 Sep. PMCID: PMC5055019  PMID: 27757353


Frankwich, K. A., J. Egnatios, M. L. Kenyon, T. R. Rutledge, P. S. Liao, S. Gupta, K. L. Herbst, and A. Zarrinpar, "Differences in Weight Loss Between Persons on Standard Balanced vs Nutrigenetic Diets in a Randomized Controlled Trial.", Clin Gastroenterol Hepatol, vol. 13, issue 9, pp. 1625-1632.e1, 2015 Sep. PMCID: PMC4546861  PMID: 25769412