Endocrinology Grand Rounds: 'Differential control of glucose metabolism by GPCR signaling pathways in hypothalamic AGRP neurons'

Join the University of Arizona Health Sciences and the Division of Endocrinology in welcoming guest lecturer, Diego Perez-Tilve, PhD, from the University of Cincinnati. Dr. Perez-Tilve will be presenting at the Endocrinology Grand Rounds.

Topic

“Differential Control of Glucose Metabolism by GPCR Signaling Pathways in Hypothalamic AGRP Neurons”

Learning Objectives

• Hypothalamic Agouti Related Protein (AGRP)-expressing neurons simultaneously, but independently, control feeding behavior and whole-body glucose homeostasis.
• Specific GPCRs (G-protein coupled receptors) signaling pathways determine the control of glucose homeostasis by AGRP neurons.
• Different branches of the Autonomic Nervous System mediate specific effects of AGRP neurons on glycemic control.

Flyer for this event:  perez-tilve_endo_grand_rounds_11.14.23.pdf

Presenter

Diego Perez-Tilve, PhD
Research Associate Professor, Department of Pharmacology and Systems Physiology
University of Cincinnati-College of Medicine

Dr. Perez-Tilve is a research associate professor in the Department of Pharmacology and Systems Physiology at the University of Cincinnati College of Medicine.

He received a doctorate in neuroendocrinology at the University of Vigo, Spain. 

His laboratory investigates the neural circuits involved in the control of energy balance in response to circulating signals such as ghrelin, leptin or GLP-1, and how the effect of those signals can be harnessed to develop therapies to treat obesity and diabetes. His research has been supported by intramural funds from the University of Cincinnati College of Medicine, the National Institutes of Health and by research collaborations with pharmaceutical companies including Novo Nordisk, MBX Biosciences, Cohbar Inc, Calibrium LLC and Hoffmann-La Roche AG.

Original event listing.