Current Grants

Study ID PI(s) Dates Organization Study Name Description
VA Merit Review Roy-Chaudhury (PI) 10/01/2013-09/30/2017 Veterans Administration Hemodynamics, Uremia and Vascular Biology: Interactive Pathways for AVF Maturation The goal of this study is to examine the impact of uremia in a pig model of AVF maturation
R01DK088777 Bercelli/Cheung/Roy-Chaudhury MPI 07/01/2011- 06/30/2016 NIH/NIDDK Hemodynamics and Vascular Wall Biology Determine Arteriovenous Fistula Maturation The major goal is to assess the impact of shear stress on venous segment stenosis
R21 EB 16737 Roy-Chaudhury (Contact PI in a MPI grant) 10/01/2013-09/30/2015 NIH/National Institute of Biomedical Imaging and Bioengineering (NIBIB) Reducing Tunneled Dialysis Catheter Dysfunction through Nitric Oxide Release The goal of this study is to develop an electrochemically modulated release system for NO in TDCs
R42DK100156 Roy-Chaudhury MPI, Stuart Contact PI 07/01/2015-06/30/2017 NIH/National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) A Luminal Vascular Coating to Reduce Time to Maturation and Failures of AV Fistulas for Hemodialysis Access The goal is to test out an endothelial protectant
PINCH Award Roy-Chaudhury as Arizona PI 02/01/2016-01/31/2016 University of Pittsburgh The Phoenix Graft The goal of this study is to develop a bioengineered graft for dialysis vascular access
NSF Engineering Research Center Sub Contract 10/01/2012-09/30/2016   Novel devices to reduce dialysis vascular access dysfunction The goal of this study is to test out special devices in a pig AV fistula model
U01 DK061028-16 Akinlolu Oluseun Ojo – PI 2001/09/28-2018/04/30 NIDDK Chronic Renal Insufficiency Cohort (CRIC) Study A total of 3,939 study participants have been followed for up to 11 years to: 1) examine the risk factors for chronic kidney disease (CKD) progression and cardiovascular disease (CVD); 2) develop predictive models to identify high risk subgroups; and 3) identify etiological factors as targets for clinical trial interventions.
U01 DK061028-16 Akinlolu Oluseun Ojo – PI 2001/09/28-2018/04/30 NIDDK Chronic Renal Insufficiency Cohort (CRIC) Study Goals of the current application are to: 1) continue the follow-up of the originally recruited CRIC cohort; 2) study the relationship between CKD and outcomes in the elderly; 3) conduct a comprehensive assessment of the morbidity experienced by participants with CKD including non- CVD clinical outcomes and non-CVD hospitalizations; and 4) recruit and prospectively evaluate CKD and CVD outcomes in participants with CKD stage 2 and 3a (mild/moderate CKD).
U54 HG006939-04 Akinlolu Oluseun Ojo – PI 2012/08/15-2017/07/31 National Human Genome Research Institute (NHGRI) H3Africa Kidney Disease Research Network An estimated 500,000-plus people succumb to end-stage renal disease annually in sub-Saharan Africa with 50 million more suffering from pre-dialysis CKD. Study objectives include: 1) phenotype 8,000 kidney disease cases and controls; 2) conduct four genetic research projects of single gene mutation kidney disorders in affected families, genetic variants of single genes associated with kidney diseases in the populations and genome-wide association studies; 3) establish two low-capital intensity, rugged and sustainable genomics research labs in Africa; 4) implement a customized six-track training and career development plan for African-based genomic researchers; 5) establish and maintain a Network-wide biospecimen repository harmonized seamlessly with the H3Africa Biorepository Grants (RFA-RM-11-011); 6) establish and maintain a network-wide data management and bioinformatics facility that integrates with the H3Africa Bioinformatics Network (RFA-RM-11-010); and 7) cooperate and coordinate Network activities with the H3Africa Consortium and NIH Program Scientists/Staff.
US13HS07689 Akinlolu Oluseun Ojo – PI 2014/09/01-2019/08/31 HRSA Reimbursement of Travel ad Subsistence Expenses for Living Organ Donation