DOM Special Lecture: ‘Senescent Cells – Emerging Therapeutic Targets for Multiple Chronic Diseases’

The Department of Medicine at the University of Arizona College of Medicine – Tucson presents:

“Senescent Cells – Emerging Therapeutic Targets for Multiple Chronic Diseases”

Joshua N. Farr, PhD

1-2 p.m., Lecture Hall Room 8403*
College of Medicine – Tucson
(See flyer below for ALL virtual viewing links.)
 

LIVESTREAM HERE!

Presenter: 
Dr. Joshua Farr is an associate research scientist in the Division of Endocrinology, Diabetes, Metabolism, and Nutrition at the Mayo Clinic College of Medicine in Rochester, Minnesota. He is also an assistant professor in the Department of Physiology and Biomedical Engineering and the Division of Gerontology. He is an active member of the Mayo Clinic Robert and Arlene Kogod Center on Aging (RAKCA).

Over the past 10 years, Dr. Farr has been working on the roles of senescent cells and their senescence-associated secretory phenotype (SASP) in mediating bone loss with aging and diabetes in mice and humans. Senescent cells are unique in that they eventually stop multiplying but don't die off when they should – continuing to release chemicals that can trigger inflammation.

Dr. Farr's group was the first to systematically identify senescent cells in the bone microenvironment with aging and to demonstrate a causal role of senescent cells in mediating age-related bone loss. He has multiple ongoing projects focused on targeting cellular senescence to extend health span, targeting cellular senescence and RAGE (receptor for advanced glycation end products) in type 2 diabetes as well as the role of p21 positive senescent cells in radiation-induced skeletal injury and repair.

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■ Flyer for this event:  dom_special_lecture_flyer_2023-12-13_v4.pdf
■ Dr. Farr’s address will be followed by a 30-minute chalk talk in DOM Conference Room 7416, located on 7th floor west of the old hospital’s main elevator bank in offices of the Division of General Internal Medicine, Geriatrics and Palliative Medicine.

For questions or accommodations that may be necessary, please contact the Office of the Chair, 520-626-6349 at least three days in advance of event.