The following published papers illustrate the latest investigative endeavors of faculty and research staff in the University of Arizona Department of Medicine and its 14 divisions. Click the PubMed links to read on about how they're setting the pace for the future of health care and precision medicine solutions to improve patient lives in Arizona and beyond.


Ayata, C., H. Kim, L. Morrison, J. K. Liao, J. Gutierrez, M. Lopez-Toledano, E. Carrazana, A. L. Rabinowicz, and I. A. Awad, "Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations.", Neurol Genet, vol. 10, issue 1, pp. e200121, 2024 Feb. PMCID: PMC10766084  PMID: 38179414


Hauer, M., A. M. Rossi, B. C. Wertheim, H. B. Kleppel, J. W. Bea, and J. L. Funk, "Dietary Supplement Use in Women Diagnosed with Breast Cancer.", J Nutr, vol. 153, issue 1, pp. 301-311, 2023 Jan. PMCID: PMC10196584  PMID: 36913466


Thiede, R. M., M. Fazel, K. M. MacDonald, and I. Abraham, "Does synthetic pharmacotherapy still have a place in treating chronic spontaneous urticaria?", Expert Opin Pharmacother, vol. 23, issue 14, pp. 1563-1567, 2022 Oct. PMID: 36173375


Cohen, J. B., T. C. Hanff, P. William, N. Sweitzer, N. R. Rosado-Santander, C. Medina, J. E. Rodriguez-Mori, N. Renna, T. I. Chang, V. Corrales-Medina, et al., "Continuation versus discontinuation of renin-angiotensin system inhibitors in patients admitted to hospital with COVID-19: a prospective, randomised, open-label trial.", Lancet Respir Med, 2021 Jan 07. PMCID: PMC7832152  PMID: 33422263
Maddox, T. M., J. L. Januzzi, L. A. Allen, K. Breathett, J. Butler, L. L. Davis, G. C. Fonarow, N. E. Ibrahim, JA. Lindenfeld, F. A. Masoudi, et al., "2021 Update to the 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee.", J Am Coll Cardiol, 2021 Jan 04. PMID: 33446410


Menon, A., A. D Perry, J. Motyka, S. Weiner, A. Standke, A. Penkevich, M. Keidan, V. B. Young, and K. Rao, "Changes in the Association between Diagnostic Testing Method, PCR Ribotype, and Clinical Outcomes from Clostridioides difficile Infection: One Institution's Experience.", Clin Infect Dis, 2020 Sep 15. PMID: 32930705
Peng, T., Y. Zong, M. Dl Johnson, S. V. Menghani, M. Lourdes Lewis, and J. N. Galgiani, "A quantitative enzyme-linked immunoassay (ELISA) to approximate complement-fixing antibody titers in serum from patients with coccidioidomycosis.", Diagn Microbiol Infect Dis, vol. 99, issue 1, pp. 115198, 2020 Sep 04. PMID: 32987245
Close, R. M., and J. B. McAuley, "Disparate Effects of Invasive Group A Streptococcus on Native Americans.", Emerg Infect Dis, vol. 26, issue 9, pp. 1971-1977, 2020 Sep. PMCID: PMC7454107  PMID: 32818411
Beatty, N. L., and S. A. Klotz, "Autochthonous Chagas Disease in the United States: How Are People Getting Infected?", Am J Trop Med Hyg, vol. 103, issue 3, pp. 967-969, 2020 Sep. PMCID: PMC7470559  PMID: 32602437
Krupp, K., P. Madhivanan, and C. M. Perez-Velez, "Should qualitative RT-PCR be used to determine release from isolation of COVID-19 patients?", J Infect, vol. 81, issue 3, pp. 452-482, 2020 Sep. PMCID: PMC7299851  PMID: 32562790
Mashaqi, S., H. M. Mansour, H. Alameddin, D. Combs, S. Patel, L. Estep, and S. Parthasarathy, "Matrix metalloproteinase-9 as a messenger in the crosstalk between obstructive sleep apnea and comorbid systemic hypertension, cardiac remodeling, and ischemic stroke: a literature review.", J Clin Sleep Med, 2020 Oct 27. PMID: 33108267
Heidenreich, P. A., G. C. Fonarow, K. Breathett, C. Y. Jurgens, B. A. Pisani, B. J. Pozehl, J. A. Spertus, K. G. Taylor, J. T. Thibodeau, C. W. Yancy, et al., "2020 ACC/AHA Clinical Performance and Quality Measures for Adults With Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures.", J Am Coll Cardiol, vol. 76, issue 21, pp. 2527-2564, 2020 Nov 24. PMID: 33153861
Alschuler, L., A. Weil, R. Horwitz, P. Stamets, A. Marie Chiasson, R. Crocker, and V. Maizes, "Integrative considerations during the COVID-19 pandemic.", Explore (NY), vol. 16, issue 6, pp. 354-356, 2020 Nov - Dec. PMCID: PMC7270871  PMID: 32229082
Adams, M., R. Bouzigard, M. Al-Obaidi, and T. T. Zangeneh, "Perinephric abscess in a renal transplant recipient due to Mycoplasma hominis: Case report and review of the literature.", Transpl Infect Dis, pp. e13308, 2020 May 07. PMID: 32378787
Miller, D. C., C. Bime, S. Partharsarathy, and J. M. Mosier, "High-Flow Oxygen Therapy Concepts: Time to Standardize Nomenclature and Avoid Confusion.", J Intensive Care Med, vol. 35, issue 5, pp. 519-523, 2020 May. PMID: 32105158
Sutcliffe, C. G., L. R. Grant, A. Reid, G. Douglass, L. B. Brown, K. Kellywood, R. C. Weatherholtz, R. Hubler, A. Quintana, R. Close, et al., "High Burden of Among Native American Individuals on the White Mountain Apache Tribal Lands.", Open Forum Infect Dis, vol. 7, issue 3, pp. ofaa061, 2020 Mar. PMCID: PMC7066796  PMID: 32190709
Mizrahi, J. D., and R. T. Shroff, "New Treatment Options for Advanced Biliary Tract Cancer.", Curr Treat Options Oncol, vol. 21, issue 8, pp. 63, 2020 Jun 29. PMID: 32602010
Jain, S. K., S. Andronikou, P. Goussard, S. Antani, D. Gomez-Pastrana, C. Delacourt, J. R. Starke, A. A. Ordonez, P. Jean-Philippe, R. S. Browning, et al., "Advanced imaging tools for childhood tuberculosis: potential applications and research needs.", Lancet Infect Dis, 2020 Jun 23. PMID: 32589869
Pu, J., F. M. Donovan, K. Ellingson, G. Leroy, J. Stone, E. Bedrick, and J. N. Galgiani, "Clinician Practice Patterns that Result in the Diagnosis of Coccidioidomycosis Before or During Hospitalization.", Clin Infect Dis, 2020 Jun 08. PMID: 32511677
Nix, D. E., J. F. Hayes, M. Al Obaidi, and T. Zangeneh, "Fixed Dosing of Amphotericin B in Morbidly Obese Individuals.", Clin Infect Dis, 2020 Jul 29. PMID: 32725197
Klotz, S. A., and J. O. Schmidt, "Autochthonous Chagas Disease. How Are These Infections Happening?", Am J Med, 2020 Jul 17. PMID: 32682868
Dhakal, B. P., N. K. Sweitzer, J. H. Indik, D. Acharya, and P. William, "SARS-CoV-2 Infection and Cardiovascular Disease: COVID-19 Heart.", Heart Lung Circ, vol. 29, issue 7, pp. 973-987, 2020 Jul. PMCID: PMC7274628  PMID: 32601020
Ellis, K. E., G. T. Nawas, C. Chan, L. York, J. Fisher, E. Connick, and T. T. Zangeneh, "Clinical Outcomes Following the Use of Archived Proviral HIV-1 DNA Genotype to Guide Antiretroviral Therapy Adjustment.", Open Forum Infect Dis, vol. 7, issue 1, pp. ofz533, 2020 Jan. PMCID: PMC6942490  PMID: 31915714
Combs, D., C-H. Hsu, O. Bailey, S. I. Patel, S. Mashaqi, L. Estep, N. Provencio-Dean, S. Lopez, and S. Parthasarathy, "Differences in sleep timing and related effects between African Americans and non-Hispanic Whites.", J Clin Sleep Med, 2020 Dec 31. PMID: 33382030
Alschuler, L., A. Marie Chiasson, R. Horwitz, E. Sternberg, R. Crocker, A. Weil, and V. Maizes, "Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease.", Explore (NY), 2020 Dec 23. PMCID: PMC7756157  PMID: 33358750
Patel, S. I., D. Combs, and S. Parthasarathy, "Sleep apnea 20/20: a 20-year cohort that continues to inform the next 20 years.", J Clin Sleep Med, vol. 16, issue S1, pp. 27-28, 2020 Dec 17. PMCID: PMC7792887  PMID: 33054968
Johnson, M. D., U. S. Younis, S. V. Menghani, K. J. Addison, M. Whalen, A. L. Pilon, A. E. Cress, F. Polverino, C. Romanoski, M. Kraft, et al., "CC16 Binding to α4β1 Integrin (VLA-4) Protects Against Infection.", Am J Respir Crit Care Med, 2020 Dec 16. PMID: 33326355
Mead, H. L., P. S. Hamm, I. N. Shaffer, M. de Melo Teixeira, C. S. Wendel, N. P. Wiederhold, G. R. Thompson, R. Muñiz-Salazar, L. Rosio Castañón-Olivares, P. Keim, et al., "Differential Thermotolerance Adaptation between Species of .", J Fungi (Basel), vol. 6, issue 4, 2020 Dec 14. PMCID: PMC7765126  PMID: 33327629
Donovan, F. M., F. A. Ramadan, S. A. Khan, A. Bhaskara, W. D. Lainhart, A. T. Narang, J. M. Mosier, K. D. Ellingson, E. J. Bedrick, M. A. Saubolle, et al., "Comparison of a Novel Rapid Lateral Flow Assay to Enzyme Immunoassay Results for Early Diagnosis of Coccidioidomycosis.", Clin Infect Dis, 2020 Aug 20. PMID: 32818956
Breathett, K. K., S. M. Knapp, P. Wightman, A. Desai, S. Mazimba, E. Calhoun, and N. K. Sweitzer, "Is the Affordable Care Act Medicaid Expansion Linked to Change in Rate of Ventricular Assist Device Implantation for Blacks and Whites?", Circ Heart Fail, vol. 13, issue 4, pp. e006544, 2020 Apr. PMCID: PMC7141778  PMID: 32233662
El-Dalati, S., I. Khurana, N. Soper, D. Cronin, M. Shea, R. L. Weinberg, J. Riddell, L. Washer, E. Shuman, J. Burke, et al., "Physician perceptions of a multidisciplinary endocarditis team.", Eur J Clin Microbiol Infect Dis, vol. 39, issue 4, pp. 735-739, 2020 Apr. PMID: 31838607
Guerra, S., E. Lombardi, D. A. Stern, D. L. Sherrill, D. Gilbertson-Dahdal, C. M. Wheatley-Guy, E. M. Snyder, A. L. Wright, F. D. Martinez, and W. J. Morgan, "Fetal Origins of Asthma: A Longitudinal Study from Birth to Age 36 Years.", Am J Respir Crit Care Med, vol. 202, issue 12, pp. 1646-1655, 2020 12 15. PMCID: PMC7737573  PMID: 32649838
Cohen, J. B., T. C. Hanff, V. Corrales-Medina, P. William, N. Renna, N. R. Rosado-Santander, J. E. Rodriguez-Mori, J. Spaak, J. Andrade-Villanueva, T. I. Chang, et al., "Randomized elimination and prolongation of ACE inhibitors and ARBs in coronavirus 2019 (REPLACE COVID) Trial Protocol.", J Clin Hypertens (Greenwich), vol. 22, issue 10, pp. 1780-1788, 2020 10. PMCID: PMC7722152  PMID: 32937008
Melén, E., G. H. Koppelman, and S. Guerra, "On Genetics, Lung Developmental Biology, and Adult Lung Function.", Am J Respir Crit Care Med, vol. 202, issue 6, pp. 791-793, 2020 09 15. PMCID: PMC7491403  PMID: 32634025
Berryhill, S., C. J. Morton, A. Dean, A. Berryhill, N. Provencio-Dean, S. I. Patel, L. Estep, D. Combs, S. Mashaqi, L. B. Gerald, et al., "Effect of wearables on sleep in healthy individuals: a randomized crossover trial and validation study.", J Clin Sleep Med, vol. 16, issue 5, pp. 775-783, 2020 05 15. PMID: 32043961
Dieterle, M. G., R. Putler, A. D Perry, A. Menon, L. Abernathy-Close, N. S. Perlman, A. Penkevich, A. Standke, M. Keidan, K. C. Vendrov, et al., "Systemic Inflammatory Mediators Are Effective Biomarkers for Predicting Adverse Outcomes in Clostridioides difficile Infection.", mBio, vol. 11, issue 3, 2020 05 05. PMCID: PMC7403776  PMID: 32371595
Rahimian, R., M. F Shirazi, J. O. Schmidt, and S. A. Klotz, "Honeybee Stings in the Era of Killer Bees: Anaphylaxis and Toxic Envenomation.", Am J Med, vol. 133, issue 5, pp. 621-626, 2020 05. PMID: 31715166
Guerra, S., and F. D. Martinez, "The Complex Beginnings of Chronic Obstructive Pulmonary Disease.", Am J Respir Crit Care Med, vol. 201, issue 6, pp. 641-642, 2020 03 15. PMCID: PMC7068834  PMID: 31899658
Behrens, N. E., A. Wertheimer, M. B. Love, S. A. Klotz, and N. Ahmad, "Evaluation of HIV-specific T-cell responses in HIV-infected older patients with controlled viremia on long-term antiretroviral therapy.", PLoS One, vol. 15, issue 9, pp. e0236320, 2020. PMCID: PMC7498024  PMID: 32941433
Latif, A., N. Lateef, F. Razzaq, V. Kapoor, M. J. Ahsan, M. Ashfaq, A. Iftikhar, F. Anwer, M. Holmberg, and P. William, "Fundamentals of Light Chain Cardiac Amyloidosis: A Focused Review.", Cardiovasc Hematol Disord Drug Targets, vol. 20, issue 4, pp. 274-283, 2020. PMID: 33256586


Galgiani, J. N., J. E. Blair, N. M. Ampel, and G. R. Thompson, "Treatment for Early, Uncomplicated Coccidioidomycosis: What is Success?", Clin Infect Dis, 2019 Sep 23. PMID: 31544210
Mashaqi, S., and D. Gozal, "Obstructive Sleep Apnea and Systemic Hypertension: Gut Dysbiosis as the Mediator?", J Clin Sleep Med, 2019 Sep 06. PMID: 31490117
Scott, A. J., and R. T. Shroff, "Moving the Needle Forward With Locoregional Treatment in Unresectable Cholangiocarcinoma-The Jury Is Still Out.", JAMA Oncol, 2019 Oct 31. PMID: 31670748
Ebong, I., and K. Breathett, "The Cardiovascular Disease Epidemic in African American Women: Recognizing and Tackling a Persistent Problem.", J Womens Health (Larchmt), 2019 Oct 29. PMID: 31661348
Shende, T. C., J. M. Fisher, C. M. Perez-Velez, A. A. Guido, K. M. Sprowl, T. M. Drake, M. L. Adelus, E. J. Bedrick, and L. E. Fantry, "PrEP Knowledge and Attitudes Among Adults Attending Public Health Clinics in Southern Arizona.", J Community Health, 2019 Oct 14. PMID: 31612368
Guerra, S., M. M. Vasquez, P. Bojang, I. N. Ramos, D. L. Sherrill, F. D. Martinez, M. Halonen, and K. S. Ramos, "Serum levels of L1-ORF1p and airflow limitation.", ERJ Open Res, vol. 5, issue 4, 2019 Oct. PMCID: PMC6876133  PMID: 31777752
Breathett, K., E. Yee, N. Pool, M. Hebdon, J. D. Crist, S. Knapp, A. Larsen, S. Solola, L. Luy, K. Herrera-Theut, et al., "Does Race Influence Decision Making for Advanced Heart Failure Therapies?", J Am Heart Assoc, vol. 8, issue 22, pp. e013592, 2019 Nov 19. PMCID: PMC6915287  PMID: 31707940
Hijmans, J. G., K. Stockelman, M'ayan. Levy, M. L Brewster, T. D. Bammert, J. J. Greiner, E. Connick, and C. A. DeSouza, "Effects of HIV-1 gp120 and TAT-derived microvesicles on endothelial cell function.", J Appl Physiol (1985), vol. 126, issue 5, pp. 1242-1249, 2019 May 01. PMCID: PMC6589811  PMID: 30789287
Flerin, N. C., A. Bardhi, J. Hua Zheng, M. Korom, J. Folkvord, C. Kovacs, E. Benko, R. Truong, T. Mota, E. Connick, et al., "Establishment of a Novel Humanized Mouse Model To Investigate Activation and Depletion of Patient-Derived HIV Latent Reservoirs.", J Virol, vol. 93, issue 6, 2019 Mar 15. PMCID: PMC6401459  PMID: 30626677
Rafikov, R., M. L. McBride, M. Zemskova, S. Kurdyukov, N. McClain, M. Niihori, P. R. Langlais, and O. Rafikova, "Inositol monophosphatase 1 as a novel interacting partner of RAGE in pulmonary hypertension.", Am J Physiol Lung Cell Mol Physiol, vol. 316, issue 3, pp. L428-L444, 2019 Mar 01. PMCID: PMC6425619  PMID: 30604625