Yves A. Lussier, MD, FACMI, a professional engineer and physician-scientist who conducts research in translational bioinformatics and personal genomics, has joined the Arizona Health Sciences Center at the University of Arizona.
Dr. Lussier will serve as UA professor of medicine; associate vice president for health sciences and chief knowledge officer for AHSC; associate director for cancer informatics and precision health for the University of Arizona Cancer Center; and associate director, BIO5 informatics, for the UA BIO5 Institute. He assumed his new duties Dec. 2.
Dr. Lussier is an international expert in translational bioinformatics and a pioneer in research informatics techniques including systems biology, data representation through ontologies and high-throughput methods in personalized medicine. At the UA, he will lead efforts to fully develop novel programs in biomedical informatics, computational genomics and precision health. Dr. Lussier will provide critical leadership in efforts to advance precision health approaches to health outcomes and healthcare delivery and in the development of big data analytical tools and resource services in support of the University’s clinical research and service missions.
“I’m extremely pleased to have Yves join the University of Arizona,” said Joe G.N. “Skip” Garcia, MD, UA senior vice president for health sciences. “Yves and his team of computational specialists bring much needed expertise and program capacity in informatics, sequence analysis, genomic annotation and computational biology that will accelerate translational research activity across campus and throughout the state.”
Anne E. Cress, PhD, interim director of the UA Cancer Center, noted that “the integration of genomics with clinical information is the key to innovative approaches to provide ‘tomorrow's medicine today’ for cancer patients. The addition of Dr. Lussier to the Cancer Center will greatly strengthen our clinical research efforts in cancer informatics and the delivery of personalized treatment plans.”
Fernando D. Martinez, MD, director of the UA BIO5 Institute, shared his enthusiasm for Dr. Lussier’s recruitment. “Informatics bridges the five core disciplines – agriculture, engineering, medicine, pharmacy and science – of BIO5. Dr. Lussier and his team will advance the Institute’s interdisciplinary, collaborative research efforts to successfully create solutions to the grand biological challenges.”
Dr. Lussier comes to UA from the University of Illinois at Chicago (UIC), where he was professor of medicine, bioengineering and biopharmaceutical sciences, and assistant vice president for health affairs and chief research information officer for the University of Illinois Hospital and Health Sciences System. Prior to his tenure at UIC, Dr. Lussier was associate director of informatics for the University of Chicago Comprehensive Cancer Center as well as co-director of biomedical informatics for the Clinical and Translational Science Award (CTSA)-funded Institute for Translational Medicine (2006-2011). From 2001-2006, Dr. Lussier was an assistant professor in the Departments of Biomedical Informatics and Medicine at Columbia University in New York.
Dr. Lussier’s research interests focus on the use of ontologies, knowledge technologies and genomic network model to accurately individualize the treatment of disease and to repurpose therapies. He has National Institutes of Health funding for a clinical trial that repositioned a combination therapy, he also bioinformatically predicted and obtained biological confirmation of several novel tumor suppressor microRNAs, including the first one underpinning the oligo- vs poly- metastasis development of cancer.
His research has been featured in the New York Times and the Wall Street Journal. He has authored 130 publications and delivered more than 100 invited presentations in precision medicine, systems medicine and translational bioinformatics, including 14 opening conference keynotes.
A Fellow of the American College of Medical Informatics, Dr. Lussier is a member of numerous governance, technology transfer, scientific and editorial boards, including the American Medical Informatics Association, International Society for Computational Biology, Society for Clinical and Translational Science, American Society for Cancer Research, Healthcare Information and Management Systems Society, American Association of Pharmaceutical Scientists, American Association for the Advancement of Science and American Society for Human Genetics.
Dr. Lussier received a bachelor of engineering and his medical degree from the University of Sherbrooke, Quebec, Canada. He performed predoctoral research in the Departments of Medicine and Human Physiology at the University of Sherbrooke. After medical school, Dr. Lussier completed an internship in ophthalmology at Laval University Hospital in Quebec City, and a residency in family medicine at the University of Sherbrooke Medical Center. He was a post-doctoral residential fellow in the Department of Biomedical Informatics in the College of Surgeons & Physicians at Columbia University.