The University of Arizona Functional Genomics Core (FGC) now is integrated with the Arizona Center for Drug Discovery, providing resources for investigators conducting research in molecular biology to run live cell, biochemical and other assays.
The FGC specializes in conducting high-throughput drug/compound screens, RNAi screens, yeast/microbial deletion library screens, and the automation of repetitive molecular biological protocols for the purpose of network analysis, drug and target discovery. Laboratory equipment also is available for general (low-throughput) use.
You’ll now also find a webpage for the FGC at the center’s website at this link.
At left, Matthew Kaplan, PhD, facilities manager for the Functional Genomics Core, and Karen Lackey, interim director of the Arizona Drug Discovery Center.
Housed in the UA College of Pharmacy, the Arizona Center for Drug Discovery (ACDD) creates the necessary infrastructure to bridge UA researchers with pharmaceutical partners to establish a collaborative environment to advance novel disease intervention findings beyond the laboratory setting. The center works with faculty members and established scientists at the UA to assemble teams around shared research projects in drug discovery and development. Faculty members also have access to mentorship and guidance regarding how to get started in drug discovery.
Construction of the $26-million, 30,000-square-foot Arizona Drug Discovery Center (see architectural rendering at right) began in September 2018 and is expected to be complete in July 2019. For updates, see this link (click on "Skaggs Building tab, top left, or Skaggs Webcam, bottom right).
If you would like to add your research to ACDD’s portfolio, complete a project proposal form and submit to Jamie McKay (mckay@pharmacy.arizona.edu). See below for a list of services, instrumentation and location, staff and lab member links.
EXTRA INFO: Drug Discovery at the UA
Additional UA resources in this area, such as computer-aided drug discovery, are hosted by the UA BIO5 Institute Drug Discovery Team as well as the following:
Therapeutic Development Team | UA Cancer Center
- Trials and Development | UA Arthritis Center
- Computational Drug Discovery | UA Center for Innovation in Brain Science
- Division of Pharmacogenomics | UA Health Sciences Center for Applied Genetics & Genomic Medicine
- Division of Translational and Regenerative Medicine | UA Department of Medicine
These are only a few of the groups and resources at the UA working on development of new pharmacological therapies to treat medical conditions. For more, visit the UA Department of Medicine Research, UA College of Medicine Research, UAHS Research Administration, UAHS Clinical Research Studies or UA’s Arizona Research Laboratories webpages. Also see our Centers & Institutes webpage.
FGC Services
- Instrument access
- High and low-throughput screening
- RNAi screening
- Drug/compound screening
- Liquid handling operations
FGC Instruments
- Biomek liquid handling robot
- Attune Acoustic Focusing Cytometer
- Singer RoToR HDA pinning robot
- BioTek Synergy 2
- Operetta CLS high-content analysis system
- Octet RED384
FGC Personnel
FGC Location
University of Arizona BIO5 Institute
Thomas W. Keating Bioresearch Building, Room 124
1657 E. Helen St.
Tucson, AZ 85721
FGC Hours
Monday – Friday, 9 a.m.-5 p.m.
Contacts
Functional Genomics Core
Matthew Kaplan, PhD, Facility Manager
(520) 626-3794 | fgc@email.arizona.edu
Arizona Center for Drug Discovery
Karen Lackey, Interim Director
(520) 626-1427 | klackey@pharmacy.arizona.edu
ALSO SEE:
"UA College of Pharmacy Establishes Arizona Center For Drug Discovery" | Posted Oct. 4, 2018