Sairam Parthasarathy, MD

  • Professor, Medicine
  • Chief, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine
  • Director, Center for Sleep and Circadian Sciences, UA Health Sciences
  • Medical Director, Center for Sleep Disorders, Banner – University Medical Center Tucson
Research Interests: 

Sleep intervention during Acute Lung Injury (R01 NIH/NHLBiHL095748):  The central purpose of this proposal is to study the short-term effects of sedation with sympatholysis on sleep and inflammation in critically ill patients with acute lung injury(ALI) and acute respiratory distress syndrome (ARDS).  Clinicaltrials.gov# NCT01050699 Positive airway pressure therapy for sleep-disordered breathing (ADVENT-HF; Canadian Institute of Health Research [CIHR] and Toronto Rehabilitation Institute, Toronto, Canada):  The central purpose of this proposal is to assess the effect of adaptive servo ventilation (ASV) on mortality and cardiovascular hospitalizations in ptients with chronic heart failure and sleep apnea.  Clinicaltrials.gov#NCT01128816 Adherence to CPAP Therapy in patients with sleep-disordered breathing (US Dept. of Veterans Affairs; PPO 10-066):  Our overall aim is to assess the feasibility and acceptability of a CPAP adherence program driven by trained "peer-buddies" with sleep apnea.  Clinicaltrials.gov# NCT01164683 Sleep deprivation in murine models (Johrei foundation):  The central purpose of this proposal is to study the sleep-promoting effects of Johrei treatment in a murine sleep deprivation model.

Degrees
  • MBBS: Madras Medical College 1990
Honors and Awards
  • Affiliate, American Academy of Sleep Medicine
  • Affiliate, Sleep Research Society
  • Affiliate, American Thoracic Society
  • Chair, Research Committee, American Academy of Sleep Medicine
  • Sleep Disorders Research Advisory Board (SDRAB), NCSDR, NIH
  • Chair, Grant Review Committee, American Sleep Medicine Foundation
  • Associate Editor, Journal of Clinical Sleep Medicine
  • Advisory Panel, US Respiratory Disease
  • Steering Committee, ADVENT-HF trial
  • Editorial Board, ACCP-SEEK Sleep Edition 2
  • Chair, DSMB, OSA and Bariatric Surgery (NIH/NHLBI)
Residency
  • Loyola University Medical Center - Chicago, Internal Medicine
Fellowship
  • Loyola University Medical Center, Pulmonary Critical Care Medicine
Board Certifications
  • American Board of Sleep Medicine, Internal Medicine - General
  • American Board of Internal Medicine, Critical Care Medicine - Subspecialty
  • American Board of Internal Medicine, Pulmonary Disease - Subspecialty
  • American Board of Internal Medicine, Sleep Medicine - Subspecialty

Select Publications

2020

Miller, D. C., C. Bime, S. Partharsarathy, and J. M. Mosier, "High-Flow Oxygen Therapy Concepts: Time to Standardize Nomenclature and Avoid Confusion.", J Intensive Care Med, vol. 35, issue 5, pp. 519-523, 2020 May. PMID: 32105158
Mashaqi, S., H. M. Mansour, H. Alameddin, D. Combs, S. Patel, L. Estep, and S. Parthasarathy, "Matrix metalloproteinase-9 as a messenger in the crosstalk between obstructive sleep apnea and comorbid systemic hypertension, cardiac remodeling, and ischemic stroke: a literature review.", J Clin Sleep Med, 2020 Oct 27. PMID: 33108267
Berryhill, S., C. J. Morton, A. Dean, A. Berryhill, N. Provencio-Dean, S. I. Patel, L. Estep, D. Combs, S. Mashaqi, L. B. Gerald, et al., "Effect of wearables on sleep in healthy individuals: a randomized crossover trial and validation study.", J Clin Sleep Med, vol. 16, issue 5, pp. 775-783, 2020 05 15. PMID: 32043961
Combs, D., C-H. Hsu, O. Bailey, S. I. Patel, S. Mashaqi, L. Estep, N. Provencio-Dean, S. Lopez, and S. Parthasarathy, "Differences in sleep timing and related effects between African Americans and non-Hispanic Whites.", J Clin Sleep Med, 2020 Dec 31. PMID: 33382030
Patel, S. I., D. Combs, and S. Parthasarathy, "Sleep apnea 20/20: a 20-year cohort that continues to inform the next 20 years.", J Clin Sleep Med, vol. 16, issue S1, pp. 27-28, 2020 Dec 17. PMCID: PMC7792887  PMID: 33054968