Drs. Laukaitis, Langlais Headline Next DOM Research Seminar on Genetics, Proteomics

NOTE: This seminar with Drs. Laukaitis and Langlais is postponed until the June 14 DOM Research Seminar. In its place on May 10, Paul Noble, MD, chair, Department of Medicine; director, Women’s Guild Lung Institute; and the Vera and Paul Guerin Family Distinguished Chair in Pulmonary Medicine, Cedars-Sinai Medical Center, Los Angeles, will speak in a joint event with the Winter Lung Series Conferences on the “Fundamentals of Idiopathic Pulmonary Fibrosis (IPF)—Navigating the Patient Journey.” Learn more here.

Flyer for May 10 DOM Research Seminar with Drs. Christina Laukaitis and Paul LanglaisTwo researchers with cross-disciplinary roots are in the lineup for an in-depth discussion on the genetics and proteomics of precision medicine solutions under development at the University of Arizona Health Sciences for the next UA Department of Medicine Research Seminar on Thursday, May 10.

The speakers are:

Christina Laukaitis, MD, PhD, UA Division of Geriatrics, General Internal and Palliative Medicine (GGP), will talk on “The hEDS GENE Study: A Major Gene-Finding Effort for Hypermobility Ehlers-Danlos Syndrome.”

The topic for Paul Langlais, PhD, UA Division of Endocrinology, is “Redefining the Effect of Insulin on Microtubules Thanks to Microtubule-Associated Proteins.”

Their lectures will be noon-1 p.m., in Room 5403 of the UA College of Medicine – Tucson. It also will be simulcast live to Conference Room 3030 at Banner – University Medical Center South. A light lunch will be served in the style of grand rounds.


You can add the event to your personal schedule (via iCal, MSOutlook, Google or Yahoo! Calendar) at this link.

For the flyer for this event, click here: dom-research-seminar_05-10-2018_flyer.pdf

To see archived video or photo galleries from previous lectures in the series, see this link.

For the last seminar on April 12, the speakers were the UA Division of Dermatology’s Vivian Shi, MD, on “The ‘Gaps’ in Eczematous Dermatoses,” and UA Valley Fever Center for Excellence Director John Galgiani, MD, on “Updating Valley Fever Serology: It’s Not World War II Anymore.” The final speakers for the series this academic year will be Nima Toosizadeh, PhD, and Yves Lussier, MD, on June 14.

About the Speakers

Christina Laukaitis, MD, PhD

Dr. Christina LaukaitisDr. Laukaitis’ research has focused on genetic and environmental risk factors that predispose individuals to cancer in order to treat neoplasia before cancer develops with an emphasis on people at high risk for breast and other cancers due to mutations in BRCA1, BRCA2, APC and mismatch repair genes. In her lab, they seek explanations for high-risk families without identified mutations. She has experience working with WBF and UDCA sample genotyping and interpreting genetic data that influences cancer risk. In addition to this research, she won an $800,000 grant in late 2016 from the Wallace Research Foundation to study the genetic basis of the joint hypermobility type of Ehlers-Danlos Syndrome, a group of inherited disorders that mostly affect the skin, joints and blood vessels. With research partners from the Division of Rheumatology, she has since received two additional smaller grants related to that research.

Promoted to associate professor last fall, Dr. Laukaitis joined the faculty at the UA College of Medicine – Tucson in 2008. She is affiliated with the UA Division of Geriatrics, General Internal and Palliative Medicine in the Department of Medicine, the Department of Nutritional Sciences in the UA College of Agriculture and Life Sciences, and the Cancer Biology and Genetics Graduate Interdisciplinary Programs. In addition, she’s director of Genetic Consultation and Counseling Services at the UA Health Sciences Center for Applied Genetics and Genomic Medicine, director of the Molecular Genetic Pathology Fellowship Program in the Department of Pathology at the UA College of Medicine – Tucson, medical education director for the Partnership for Native American Cancer Prevention at the UA Cancer Center and a member of the UA Center on Aging as well as the Southwest Environmental Health Sciences Center at the UA College of Pharmacy.

Among her honors and recognitions, Dr. Laukaitis was a member of the COM-T Learning to Lead Faculty Leadership Program (2014-15), named Researcher of the Year by the Arizona Chapter of the American College of Physicians (2013), among the Arizona Daily Star's “40 under 40” up-and-coming professionals (2011), winner of the Yellen Distinguished Young Investigator Award at the UA Cancer Center (2011), and chosen to participate in the Alliance for Academic Internal Medicine’s T. Franklin Williams Scholars Program in Washington, DC (2011). In addition, she was a visiting researcher at Oxford University and winner of the American Medical Women’s Association’s Janet M. Glasgow Award (Summer 2003).

She has served on multiple committees related to genetic, genomic, molecular and precision medicine research at the UA College of Medicine, UA Health Sciences and the broader UA campus. She, currently, is a member of the college’s Multidisciplinary Endocrine Tumor Board and MD/PhD Program Admissions Committee, organizer of the college’s Genetics & Genomics Grand Rounds, and an ad hoc member of the UA Cancer Center’s Scientific Review Committee. And she has contributed to several scholarly book chapters and monographs and authored or co-authored more than 30 refereed journal articles and 28 abstracts.

Before coming to the UA, Dr. Laukaitis was a fellow in the Division of Medical Genetics at the University of Washington in Seattle. She completed her residency in internal medicine at St. Vincent’s Hospital in Indianapolis, where she was affiliated with the Butler Summer Institute at Butler University. She earned her medical degree from the University of Chicago College of Medicine – Champaign-Urbana Campus. Her doctorate is in cell and structural biology from the University of Illinois. Her bachelor’s degree is in chemistry from Butler University.

Paul Langlais, PhD

Dr. Paul LanglaisDr. Langlais is an associate professor of medicine in the Division of Endocrinology, director of the Proteomics Lab and a member of the Center for Disparities in Diabetes, Obesity and Metabolism at the UA Health Sciences. He joined the faculty at the UA College of Medicine – Tucson in 2016, having served previously as an assistant professor and proteomics lab director at Mayo Scottsdale and, before that, as an assistant research professor and director, Center for Metabolic and Vascular Biology Proteomics Lab, Arizona State University—where he also completed a post-doctoral research fellowship. He holds a bachelor’s degree in biology and chemistry from Texas Tech University and a doctorate in biochemistry from the University of Texas Health Science Center at San Antonio.

For more than 20 years, Dr. Langlais has performed discovery-based research in the field of insulin signal transduction. He is very proficient at mass spectrometry-based, label-free quantitative proteomics, i.e., adaptation of mass spectrometry to the quantification of protein post-translational modification levels and/or protein expression levels among groups and/or treatments. He is able to explore protein-protein associations via interactome characterization. He has extensive experience in researching the role proteins play in the insulin signal transduction cascade, and how these proteins are regulated by either post-translational modification or by protein-protein interactions. Beyond that, he also specializes in contributing quantitative proteomics experiments to collaborators in need of this technique.

About the DOM Research Seminar Series

The brainchild of DOM Chair Monica Kraft, MD, and Vice Chair for Research Jil Tardiff, MD, PhD, UA Department of Medicine Research Seminar Series began in September 2016 as a way to showcase the remarkable breadth of medical research conducted at the University of Arizona. It pairs a junior and senior investigator from different divisions who each speak for 20-25 minutes followed by Q&A sessions. It is held on the second Thursday of the month between September and June, noon-1 p.m., UAHS Room 5403. A light lunch is served in the style of grand rounds. Learn more here: http://deptmedicine.arizona.edu/research/department-medicine-research-se...

CONTACT: Claudia Duran, Sr. Prog. Coordinator, DOM Office of the Chair, (520) 626-6349 or crduran@deptofmed.arizona.edu

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Release Date: 
04/16/2018 - 4:45pm