Sas KM, Lin J, Rajendiran TM, Soni T, Nair V, Hinder LM, Jagadish HV, Gardner TW, Abcouwer SF, Brosius FC 3rd, Feldman EL, Kretzler M, Michailidis G, Pennathur S. Shared and distinct lipid-lipid interactions in plasma and affected tissues in a diabetic mouse model. J Lipid Res. J Lipid Res. 2018 Feb;59(2):173-183.
Tuttle KR, Brosius FC 3rd*, Adler SG, Kretzler M, Mehta RL, Tumlin JA, Tanaka Y, Haneda M, Liu J, Silk ME, Cardillo TE, Duffin KL, Haas JV, Macias WL, Nunes FP, Janes JM. JAK1/JAK2 Inhibition by Baricitinib in Diabetic Kidney Disease: Results from a Phase 2 Randomized Controlled Clinical Trial (*co-first and co-corresponding author), Nephrol Dial Transplant. 2018; Feb 22. doi: 10.1093/ndt/gfx377. [Epub ahead of print]
Brosius FC, Jun W. The Promise of System Biology for Diabetic Kidney Disease. Adv Chronic Kidney Dis. 2018;25(2):202-213
Mathew A, Atkins K, Brosius FC, Pennathur S. Myeloperoxidase Derived Oxidants Damage Artery Wall Proteins in an Animal Model of Chronic Kidney Disease Accelerated Atherosclerosis. J Biol Chem. 2018;11;293(19):7238-7249
Tuegel C, Katz R, Alam M, Bhat Z, Bellovich K, de Boer I, Brosius F, Gadegbeku C, Gipson D, Hawkins J, Himmelfarb J, Ju W, Kestenbaum B, Kretzler M, Robinson-Cohen C, Steigerwalt S, Bansal N. Growth differentiation factor-15, Galectin-3, and Soluble ST-2 and Risk of Mortality and Cardiovascular Events in Chronic Kidney Disease. Am J Kidney Dis, 2018; pii: S0272-6386(18)30636-X. doi: 10.1053/j.ajkd.2018.03.025. [Epub ahead of print]
Bakhtar O, Thajudeen B, Sussman A. Decreasing After-Hours Hemodialysis in Hospitals. Ther Apher Dial. 2016;20(1):87-8.
Howlader A, Thajudeen B, Sussman AN, Bracamonte E, Krahl L, Nasr SH. Proliferative Glomerulonephritis With Masked Monoclonal Deposits Responsive to Myeloma Therapy. Kidney Int Rep. 2017;2(6):1233-1237.
Kaur G, Thajudeen B. Asymptomatic bilateral giant angiomyolipoma. Saudi J Kidney Dis Transpl. 2017;28(3):675-677.
Kaur G, Bijin B, Saleem K, Sarsah B, Thajudeen B. Leukocyte Cell-Derived Chemotaxin 2-Associated Renal Amyloidosis: A Case Report. Case Rep Nephrol Dial. 2017;7(2):121-129.
Moinuddin I, Thajudeen B, Sussman A, et al. Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis. Case Rep Transplant. 2016;2016:4603014.
Moinuddin I, Madhrira M, Bracamonte E, Thajudeen B, Sussman A. Membranous nephropathy with crescents associated with levamisole-induced MPO-ANCA vasculitis. Pathol Res Pract. 2016;212(7):650-3.
Murugapandian S, Mansour I, Hudeeb M, et al. Epidemiology of Glomerular Disease in Southern Arizona: Review of 10-Year Renal Biopsy Data. Medicine (Baltimore). 2016;95(18):e3633.
Sardar A, Thajudeen B, Kadambi PV. Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal Dialysis.Case Rep Nephrol. 2018 May 10;2018:8015230. doi: 10.1155/2018/8015230. PMID 29862101\
Thajudeen B, Salahudeen AK. Role of tolvaptan in the management of hyponatremia in patients with lung and other cancers: current data and future perspectives. Cancer Manag Res. 2016;8:105-14.
Howlader A, Thajudeen B, Sussman AN, Bracamonte E, Krahl L, Nasr SH. Proliferative Glomerulonephritis With Masked Monoclonal Deposits Responsive to Myeloma Therapy. Kidney Int Rep. 2017;2(6):1233-1237.
Moinuddin I, Thajudeen B, Sussman A, et al. Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis. Case Rep Transplant. 2016;2016:4603014.
Moinuddin I, Madhrira M, Bracamonte E, Thajudeen B, Sussman A. Membranous nephropathy with crescents associated with levamisole-induced MPO-ANCA vasculitis. Pathol Res Pract. 2016;212(7):650-3.
Bakhtar O, Thajudeen B, Sussman A. Decreasing After-Hours Hemodialysis in Hospitals. Ther Apher Dial. 2016;20(1):87-8.
Murugapandian S, Mansour I, Hudeeb M, et al. Epidemiology of Glomerular Disease in Southern Arizona: Review of 10-Year Renal Biopsy Data. Medicine (Baltimore). 2016;95(18):e3633.
Murugapandian S, Bijin B, Mansour I, et al. Improvement in Gemcitabine-Induced Thrombotic Microangiopathy with Rituximab in a Patient with Ovarian Cancer: Mechanistic Considerations. Case Rep Nephrol Dial. 2015;5(2):160-7.
Shanmugasundaram M, Murugapandian S, Truong HT, Lotun K, Banerjee S. Drug coated balloon in peripheral artery disease. Cardiovasc Revasc Med. 2018;
Brooks HL, Lindsey ML. Guidelines for authors and reviewers on antibody use in physiology studies. Am J Physiol Heart Circ Physiol. 2018;314(4):H724-H732.
Irsik DL, Romero-Aleshire MJ, Chavez EM, Fallet RW, Brooks HL, Carmines PK, Lane PH. Renoprotective impact of estrogen receptor-α and its splice variants in female mice with type 1 diabetes. Am J Physiol Renal Physiol. 2018;315(3):F512-F520.
Small DM, Sanchez WY, Roy SF, Morais C, Brooks HL, Coombes JS, Johnson DW, Gobe GC. N-acetyl-cysteine increases cellular dysfunction in progressive chronic kidney damage after acute kidney injury by dampening endogenous antioxidant responses. Am J Physiol Renal Physiol. 2018;314(5):F956-F968.
Poulsen SB, Kristensen TB, Brooks HL, Kohan DE, Rieg T, Fenton RA. Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus. JCI Insight. 2017;2(7):e91042.
Bhargava P, Schnellmann RG. Mitochondrial energetics in the kidney. Nat Rev Nephrol. 2017;13(10):629-646.
Cameron RB, Beeson CC, Schnellmann RG. Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases. J Med Chem. 2016;59(23):10411-10434.
Cameron RB, Beeson CC, Schnellmann RG. Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol. Sci Rep. 2017;7(1):10578.
Collier JB, Schnellmann RG. Extracellular Signal-Regulated Kinase 1/2 Regulates Kidney Injury Molecule-1 Expression Physiologically and Following Ischemic and Septic Renal Injury. J Pharmacol Exp Ther. 2017;
Collier JB, Whitaker RM, Eblen ST, Schnellmann RG. Rapid Renal Regulation of Peroxisome Proliferator-activated Receptor γ Coactivator-1α by Extracellular Signal-Regulated Kinase 1/2 in Physiological and Pathological Conditions. J Biol Chem. 2016;291(52):26850-26859.
Dupre TV, Doll MA, Shah PP, et al. Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury. J Lipid Res. 2017;58(7):1439-1452.
Dupre TV, Doll MA, Shah PP, et al. Suramin protects from cisplatin-induced acute kidney injury. Am J Physiol Renal Physiol. 2016;310(3):F248-58.
Gibbs WS, Collier JB, Morris M, Beeson CC, Megyesi J, Schnellmann RG. 5-HT receptor regulates mitochondrial homeostasis and its loss potentiates acute kidney injury and impairs renal recovery. Am J Physiol Renal Physiol. 2018;315(4):F1119-F1128.
Gibbs WS, Garrett SM, Beeson CC, Schnellmann RG. Identification of dual mechanisms mediating 5-hydroxytryptamine receptor 1F-induced mitochondrial biogenesis. Am J Physiol Renal Physiol. 2018;314(2):F260-F268.
Gibbs WS, Weber RA, Schnellmann RG, Adkins DL. Disrupted mitochondrial genes and inflammation following stroke. Life Sci. 2016;166:139-148.
Krishnasamy Y, Ramshesh VK, Gooz M, Schnellmann RG, Lemasters JJ, Zhong Z. Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice. PLoS ONE. 2016;11(9):e0163342.
Harmon JL, Gibbs WS, Whitaker RM, Schnellmann RG, Adkins DL. Striatal Mitochondrial Disruption following Severe Traumatic Brain Injury. J Neurotrauma. 2017;34(2):487-494.
Harmon JL, Wills LP, Mcomish CE, et al. 5-HT2 Receptor Regulation of Mitochondrial Genes: Unexpected Pharmacological Effects of Agonists and Antagonists. J Pharmacol Exp Ther. 2016;357(1):1-9.
Rehman H, Liu Q, Krishnasamy Y, et al. The mitochondria-targeted antioxidant MitoQ attenuates liver fibrosis in mice. Int J Physiol Pathophysiol Pharmacol. 2016;8(1):14-27.
Schnellmann R. Resistin Resets Neutrophil Function in Kidney Diseases. Crit Care Med. 2016;44(7):1454-5.
Scholpa NE, Williams H, Wang W, et al. Pharmacological stimulation of mitochondrial biogenesis using the FDA-approved β<sub>2</sub>-adrenoreceptor agonist formoterol for the treatment of spinal cord injury. J Neurotrauma. 2018;
Scholpa NE, Lynn MK, Corum D, Boger HA, Schnellmann RG. 5-HT receptor-mediated mitochondrial biogenesis for the treatment of Parkinson's disease. Br J Pharmacol. 2018;175(2):348-358.
Scholpa NE, Schnellmann RG. Mitochondrial-Based Therapeutics for the Treatment of Spinal Cord Injury: Mitochondrial Biogenesis as a Potential Pharmacological Target. J Pharmacol Exp Ther. 2017;363(3):303-313.
Smith JA, Mayeux PR, Schnellmann RG. Delayed Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Inhibition by Trametinib Attenuates Systemic Inflammatory Responses and Multiple Organ Injury in Murine Sepsis. Crit Care Med. 2016;44(8):e711-20.
Whitaker RM, Corum D, Beeson CC, Schnellmann RG. Mitochondrial Biogenesis as a Pharmacological Target: A New Approach to Acute and Chronic Diseases. Annu Rev Pharmacol Toxicol. 2016;56:229-49.
2016-2017 Publications
Nair V, Robinson-Cohen C, Smith MR, Bellovich KA, Bhat ZY, Bobadilla M, Brosius F, de Boer IH, Essioux L, Formentini I, Gadegbeku CA, Gipson D, Hawkins J, Himmelfarb J, Kestenbaum B, Kretzler M, Magnone MC, Perumal K, Steigerwalt S, Ju W, Bansal N. J. Growth Differentiation Factor-15 and Risk of CKD Progression. J Am Soc Nephrol. 2017 July;28(7):2233-2240.
Zhang H, Nair V, Saha J, Atkins KB, Hodgin JB, Saunders TL, Myers MG Jr, Werner T, Kretzler M, Brosius FC. Podocyte-specific JAK2 Overexpression Worsens Diabetic Kidney Disease in Mice. Kidney International, 2017 May 26.
Dupre TV, Doll MA, Shah PP, Sharp CN, Siow D, Megyesi J, Shayman J, Bielawska A, Bielawski J, Beverly LJ, Hernandez-Corbacho M, Clarke CJ, Snider AJ, Schnellmann RG, Obeid LM, Hannun YA, Siskind LJ. Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury. J Lipid Res. 2017 Jul;58(7):1439-1452. doi: 10.1194/jlr.M076745. Epub 2017 May 10.
O'Brien PD, Hinder LM, Parlee SD, Hayes JM, Backus C, Zhang H, Ma L, Sakowski SA, Brosius FC 3rd, Feldman EL. Dual CCR2/CCR5 antagonist treatment attenuates adipose inflammation, but not microvascular complications in ob/ob mice. Diabetes Obes Metab. 2017 Mar 23. [Epub ahead of print].
Park M, Rumora AE, Hinder LM, Hur J, Eichinger F, Pennathur S, Kretzler M, Brosius FC 3rd, Feldman EL. Comparative RNA-Seq Transcriptome Analyses Reveal Distinct Metabolic Pathways in Diabetic Nerve and Kidney Disease. J Cell Mol Med, 2017 Mar 8.
Collier JB, Whitaker RM, Eblen ST, Schnellmann RG. Rapid Renal Regulation of Peroxisome Proliferator-activated Receptor γ Coactivator-1α by Extracellular Signal-Regulated Kinase 1/2 in Physiological and Pathological Conditions. J Biol Chem. 2016 Dec 23;291(52):26850-26859. doi: 10.1074/jbc.M116.754762. Epub 2016 Nov 14.
Gibbs WS, Weber RA, Schnellmann RG, Adkins DL. Disrupted mitochondrial genes and inflammation following stroke. Life Sci. 2016 Dec 1;166:139-148. doi: 10.1016/j.lfs.2016.09.021. Epub 2016 Sep 28.
Krishnasamy Y, Ramshesh VK, Gooz M, Schnellmann RG, Lemasters JJ, Zhong Z. Ethanol and High Cholesterol Diet Causes Severe Steatohepatitis and Early Liver Fibrosis in Mice. PLoS One. 2016 Sep 27;11(9):e0163342. doi: 10.1371/journal.pone.0163342. eCollection 2016.
Cameron RB, Beeson CC, Schnellmann RG. Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases. J Med Chem. 2016 Dec 8;59(23):10411-10434. Epub 2016 Sep 27. Review.
Harmon JL, Gibbs WS, Whitaker RM, Schnellmann RG, Adkins DL. Striatal Mitochondrial Disruption following Severe Traumatic Brain Injury. J Neurotrauma. 2017 Jan 15;34(2):487-494. doi: 10.1089/neu.2015.4395. Epub 2016 Aug 1.
Murugapandian S, Mansour I, Hudeeb M, Hamed K, Hammode E, Bijin B, Daheshpour S, Thajudeen B, Kadambi P. Epidemiology of Glomerular Disease in Southern Arizona: Review of 10-Year Renal Biopsy Data. Medicine (Baltimore). 2016 May;95(18):e3633. doi: 10.1097/MD.0000000000003633. PMID: 27149502