The following published papers illustrate the latest investigative endeavors of faculty and research staff in the University of Arizona Department of Medicine and its 14 divisions. Click the PubMed links to read on about how they're setting the pace for the future of health care and precision medicine solutions to improve patient lives in Arizona and beyond.


Willis, W. T., D. Miranda-Grandjean, J. Hudgens, E. A. Willis, J. Finlayson, E. A. De Filippis, Z. R Bustos, P. R. Langlais, C. Mielke, and L. J. Mandarino, "Dominant and sensitive control of oxidative flux by the ATP-ADP carrier in human skeletal muscle mitochondria: Effect of lysine acetylation.", Arch Biochem Biophys, vol. 647, pp. 93-103, 2018 06 01. PMID: 29653079
Almodovar, S., J. Swanson, L. D. Giavedoni, S. Kanthaswamy, C. S. Long, N. F. Voelkel, M. G. Edwards, J. M. Folkvord, E. Connick, S. V. Westmoreland, et al., "Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines in SHIVnef-Infected Macaques.", Viral Immunol, vol. 31, issue 3, pp. 206-222, 2018 04. PMCID: PMC5909115  PMID: 29256819
Webb, G. M., S. Li, G. Mwakalundwa, J. M. Folkvord, J. M. Greene, J. S. Reed, J. J. Stanton, A. W. Legasse, T. Hobbs, L. D. Martin, et al., "The human IL-15 superagonist ALT-803 directs SIV-specific CD8 T cells into B-cell follicles.", Blood Adv, vol. 2, issue 2, pp. 76-84, 2018 01 23. PMCID: PMC5787870  PMID: 29365313
Bronnimann, M. P., P. J. Skinner, and E. Connick, "The B-Cell Follicle in HIV Infection: Barrier to a Cure.", Front Immunol, vol. 9, pp. 20, 2018. PMCID: PMC5788973  PMID: 29422894
Merchant, J. L., "Parietal Cell Death by Cytokines.", Cell Mol Gastroenterol Hepatol, vol. 5, issue 4, pp. 636-637, 2018. PMCID: PMC5924744  PMID: 29713663
Engineer, A., E. M. Sternberg, and B. Najafi, "Designing Interiors to Mitigate Physical and Cognitive Deficits Related to Aging and to Promote Longevity in Older Adults: A Review.", Gerontology, vol. 64, issue 6, pp. 612-622, 2018. PMID: 30130764
Razumilava, N., D. L. Gumucio, L. C. Samuelson, Y. M. Shah, A. Nusrat, and J. L. Merchant, "Indian Hedgehog Suppresses Intestinal Inflammation.", Cell Mol Gastroenterol Hepatol, vol. 5, issue 1, pp. 63-64, 2018. PMCID: PMC5736880  PMID: 29276751
Robbins, R., A. Seixas, G. Jean-Louis, S. Parthasarathy, D. M. Rapoport, G. Ogedegbe, and J. A. Ladapo, "National patterns of physician management of sleep apnea and treatment among patients with hypertension.", PLoS One, vol. 13, issue 5, pp. e0196981, 2018. PMCID: PMC5965818  PMID: 29791455
Foote, F. O., H. Benson, A. Berger, B. Berman, J. DeLeo, P. A. Deuster, D. J. Lary, M. N. Silverman, and E. M. Sternberg, "Advanced Metrics for Assessing Holistic Care: The "Epidaurus 2" Project.", Glob Adv Health Med, vol. 7, pp. 2164957X18755981, 2018. PMCID: PMC5824899  PMID: 29497586


Herbst, K. L., C. Ussery, and A. Eekema, "Pilot study: whole body manual subcutaneous adipose tissue (SAT) therapy improved pain and SAT structure in women with lipedema.", Horm Mol Biol Clin Investig, vol. 33, issue 2, 2017 Sep 20. PMID: 28930626
Kruse, R., J. Krantz, N. Barker, R. L. Coletta, R. Rafikov, M. Luo, K. Højlund, L. J. Mandarino, and P. R. Langlais, "Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein.", Mol Cell Proteomics, vol. 16, issue 10, pp. 1718-1735, 2017 Oct. PMCID: PMC5629260  PMID: 28550165
Indik, J. H., K. K. Patton, M. Beardsall, C. A. Chen-Scarabelli, M. I. Cohen, T-M. L. Dickfeld, D. E. Haines, R. H. Helm, K. Krishnan, J. Cosedis Nielsen, et al., "HRS Clinical Document Development Methodology Manual and Policies: Executive summary.", Heart Rhythm, vol. 14, issue 10, pp. e495-e500, 2017 Oct. PMID: 28965612
Tracy, C. M., G. H. Crossley, J. T Bunch, G. V. Chow, A. Leiserowitz, J. H. Indik, F. Kusumoto, L. A. Mendes, T. M. Munger, S. Murali, et al., "2017 ACC/HRS Lifelong Learning Statement for Clinical Cardiac Electrophysiology Specialists: A Report of the ACC Competency Management Committee.", J Am Coll Cardiol, 2017 Nov 15. PMID: 29191467
Ocadiz-Ruiz, R., A. L. Photenhauer, M. M. Hayes, L. Ding, E. R. Fearon, and J. L. Merchant, "ZBP-89 function in colonic stem cells and during butyrate-induced senescence.", Oncotarget, vol. 8, issue 55, pp. 94330-94344, 2017 Nov 07. PMCID: PMC5706877  PMID: 29212231
Vaughn, A. R., P. Tannhauser, R. K. Sivamani, and V. Y. Shi, "Mother Nature in Eczema: Maternal Factors Influencing Atopic Dermatitis.", Pediatr Dermatol, vol. 34, issue 3, pp. 240-246, 2017 May. PMID: 28523877
Ding, Q., I. Subramanian, T. R. Luckhardt, P. Che, M. Waghray, X. Zhao, N. Bone, A. R. Kurundkar, L. Hecker, M. Hu, et al., "Focal Adhesion Kinase Signaling Determines the Fate of Lung Epithelial Cells in Response to TGF-β.", Am J Physiol Lung Cell Mol Physiol, pp. ajplung.00121.2016, 2017 Mar 30. PMID: 28360109
Bauman, J. E., U. Duvvuri, W. E. Gooding, T. J. Rath, N. D. Gross, J. Song, A. Jimeno, W. G. Yarbrough, F. M. Johnson, L. Wang, et al., "Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer.", JCI Insight, vol. 2, issue 6, pp. e90449, 2017 Mar 23. PMCID: PMC5358497  PMID: 28352657
Song, S., R. J. Ayon, A. Yamamura, H. Yamamura, S. Dash, A. Babicheva, H. Tang, X. Sun, A. G. Cordery, Z. Khalpey, et al., "Capsaicin-induced Ca(2+) signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH.", Am J Physiol Lung Cell Mol Physiol, vol. 312, issue 3, pp. L309-L325, 2017 Mar 01. PMID: 27979859
Palumbo, S., Y-J. Shin, K. Ahmad, A. A. Desai, H. Quijada, M. Mohamed, A. Knox, S. Sammani, B. A. Colson, T. Wang, et al., "Dysregulated Nox4 ubiquitination contributes to redox imbalance and age-related severity of acute lung injury.", Am J Physiol Lung Cell Mol Physiol, vol. 312, issue 3, pp. L297-L308, 2017 Mar 01. PMID: 28062482
Katial, R. K., G. W. Bensch, W. W. Busse, B. E. Chipps, J. L. Denson, A. N. Gerber, J. S. Jacobs, M. Kraft, R. J. Martin, P. Nair, et al., "Changing Paradigms in the Treatment of Severe Asthma: The Role of Biologic Therapies.", J Allergy Clin Immunol Pract, vol. 5, issue 2S, pp. S1-S14, 2017 Mar - Apr. PMID: 28143691
Joseph, B., T. Orouji Jokar, A. Hassan, A. Azim, M. Jane Mohler, N. Kulvatunyou, S. Siddiqi, H. Phelan, M. Fain, and P. Rhee, "Redefining the association between old age and poor outcomes after trauma: The impact of frailty syndrome.", J Trauma Acute Care Surg, vol. 82, issue 3, pp. 575-581, 2017 Mar. PMID: 28225741
Zhang, Y., L. Wang, Y. Zi, L. Zhang, Y. Guo, and Y. Huang, "Oridonin effectively reverses the drug resistance of cisplatin involving induction of cell apoptosis and inhibition of MMP expression in human acute myeloid leukemia cells.", Saudi J Biol Sci, vol. 24, issue 3, pp. 678-686, 2017 Mar. PMCID: PMC5372424  PMID: 28386196
Addison, K. J., J. Morse, A. Robichaud, M. O. Daines, and J. G. Ledford, "A Novel in vivo System to Test Bronchodilators.", J Infect Pulm Dis, vol. 3, issue 1, 2017 Mar. PMID: 28367537
Tager, D., A. Hatch, J. Segar, B. Roller, M. Al Mohajer, and T. T. Zangeneh, "Coccidioidal meningitis complicated by central nervous system vasculitis in a patient with leukemia.", Med Mycol Case Rep, vol. 16, pp. 8-11, 2017 Jun. PMCID: PMC5374848  PMID: 28386527
Trusler, A. R., A. K. Clark, R. K. Sivamani, and V. Y. Shi, "The Endocannabinoid System and Its Role in Eczematous Dermatoses.", Dermatitis, vol. 28, issue 1, pp. 22-32, 2017 Jan/Feb. PMID: 28098721
Tey, K. Rou, A. Aggarwal, and B. Banerjee, "Migrating coil.", BMJ Case Rep, vol. 2017, 2017 Jan 27. PMID: 28130285
Kumar, iv, S., X. Sun, S. Kumar Noonepalle, Q. Lu, E. Zemskov, T. Wang, S. Aggarwal, C. Gross, S. Sharma, A. A. Desai, et al., "Hyper-activation of pp60(Src) limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury.", Free Radic Biol Med, vol. 102, pp. 217-228, 2017 Jan. PMID: 27838434
Chen, J., J. R. Sysol, S. Singla, S. Zhao, A. Yamamura, D. Valdez-Jasso, T. Abbasi, K. M. Shioura, S. Sahni, V. Reddy, et al., "Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and is a Therapeutic Target in Pulmonary Arterial Hypertension.", Circulation, 2017 Feb 15. PMID: 28202489
Huang, Y., S-F. Ma, M. S. Espindola, R. Vij, J. M. Oldham, G. B. Huffnagle, J. R. Erb-Downward, K. R. Flaherty, B. B. Moore, E. S. White, et al., "Microbes Associate with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis.", Am J Respir Crit Care Med, 2017 Feb 03. PMID: 28157391
Su, X., X. Qiao, J. Li, L. Gao, C. Wang, and L. Wang, "Papulonodular mucinosis, Guillain-Barré syndrome and nephrotic syndrome in a patient with systemic lupus erythematosus: a case report.", BMC Nephrol, vol. 18, issue 1, pp. 43, 2017 Feb 01. PMCID: PMC5286654  PMID: 28143420
Infante, J. R., A. Patnaik, C. F. Verschraegen, A. J. Olszanski, M. Shaheen, H. A. Burris, A. W. Tolcher, K. P. Papadopoulos, M. Beeram, S. M. Hynes, et al., "Two Phase 1 dose-escalation studies exploring multiple regimens of litronesib (LY2523355), an Eg5 inhibitor, in patients with advanced cancer.", Cancer Chemother Pharmacol, vol. 79, issue 2, pp. 315-326, 2017 Feb. PMID: 28097385
Kartan, S., V. Y. Shi, A. K. Clark, and L. S. Chan, "Paraneoplastic Pemphigus and Autoimmune Blistering Diseases Associated with Neoplasm: Characteristics, Diagnosis, Associated Neoplasms, Proposed Pathogenesis, Treatment.", Am J Clin Dermatol, vol. 18, issue 1, pp. 105-126, 2017 Feb. PMID: 27878477
Odio, C. D., B. E. Marciano, J. N. Galgiani, and S. M. Holland, "Risk Factors for Disseminated Coccidioidomycosis, United States.", Emerg Infect Dis, vol. 23, issue 2, 2017 Feb. PMCID: PMC5324825  PMID: 28098554
Ebner, L., M. He, R. S. Virgincar, T. Heacock, S. S. Kaushik, M. S. Freemann, P. H McAdams, M. Kraft, and B. Driehuys, "Hyperpolarized 129Xenon Magnetic Resonance Imaging to Quantify Regional Ventilation Differences in Mild to Moderate Asthma: A Prospective Comparison Between Semiautomated Ventilation Defect Percentage Calculation and Pulmonary Function Tests.", Invest Radiol, vol. 52, issue 2, pp. 120-127, 2017 Feb. PMID: 27662575
Li, Q., G. A Schissler, V. Gardeux, J. Berghout, I. Achour, C. Kenost, H. Li, H. Helen Zhang, and Y. A. Lussier, "kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects.", J Biomed Inform, vol. 66, pp. 32-41, 2017 Feb. PMCID: PMC5316373  PMID: 28007582
Donovan, F. M., T. T. Zangeneh, J. Malo, and J. N. Galgiani, "Top Questions in the Diagnosis and Treatment of Coccidioidomycosis.", Open Forum Infect Dis, vol. 4, issue 4, pp. ofx197, 2017 Fall. PMCID: PMC5903411  PMID: 29670928
Mashaqi, S., J. Hennessy, M. Eaton, and J. Erickson, "Obstructive Sleep Apnea in a Patient with Cornelia de Lange Syndrome.", Cureus, vol. 9, issue 12, pp. e1993, 2017 Dec 28. PMCID: PMC5832399  PMID: 29507843
Derkac, W. M., J. R. Finkelmeier, D. J. Horgan, and M. D. Hutchinson, "Diagnostic yield of asymptomatic arrhythmias detected by mobile cardiac outpatient telemetry and autotrigger looping event cardiac monitors.", J Cardiovasc Electrophysiol, vol. 28, issue 12, pp. 1475-1478, 2017 Dec. PMID: 28940881
Kalb, B., J. H. Indik, P. Ott, and D. R. Martin, "MRI of patients with implanted cardiac devices.", J Magn Reson Imaging, 2017 Aug 04. PMID: 28776823
Liang, J. J., B. P. Betensky, D. Muser, E. S. Zado, E. Anter, N. D. Desai, D. J. Callans, R. Deo, D. S. Frankel, M. D. Hutchinson, et al., "Long-term outcome of surgical cryoablation for refractory ventricular tachycardia in patients with non-ischemic cardiomyopathy.", Europace, 2017 Apr 10. PMID: 28402404
Wang, T., C. Gross, A. A. Desai, E. Zemskov, X. Wu, A. N. Garcia, J. R. Jacobson, J. X. - J. Yuan, J. G. N. Garcia, and S. M. Black, "Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets.", Am J Physiol Lung Cell Mol Physiol, vol. 312, issue 4, pp. L452-L476, 2017 Apr 01. PMID: 27979857
Bauman, J. E., E. Cohen, R. L. Ferris, D. J. Adelstein, D. M. Brizel, J. A. Ridge, B. O'Sullivan, B. A. Burtness, L. H. Butterfield, W. E. Carson, et al., "Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting.", Cancer, vol. 123, issue 7, pp. 1259-1271, 2017 Apr 01. PMID: 27906454
Sundaresan, S., C. A. Meininger, A. J. Kang, A. L. Photenhauer, M. M. Hayes, N. Sahoo, J. Grembecka, T. Cierpicki, L. Ding, T. J. Giordano, et al., "Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells.", Gastroenterology, vol. 153, issue 6, pp. 1555-1567.e15, 2017 12. PMCID: PMC5705278  PMID: 28859856
Miller, S. M., B. Miles, K. Guo, J. Folkvord, A. L. Meditz, M. D. McCarter, D. N. Levy, S. MaWhinney, M. L. Santiago, and E. Connick, "Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1.", J Virol, vol. 91, issue 17, 2017 09 01. PMCID: PMC5553166  PMID: 28615202
Ostrosky-Zeichner, L., and M. Al-Obaidi, "Invasive Fungal Infections in the Intensive Care Unit.", Infect Dis Clin North Am, vol. 31, issue 3, pp. 475-487, 2017 09. PMID: 28687215
Shetty, S., A. Fernandes, S. Patel, D. Combs, M. A. Grandner, and S. Parthasarathy, "Unanticipated Nocturnal Oxygen Requirement during Positive Pressure Therapy for Sleep Apnea and Medical Comorbidities.", J Clin Sleep Med, vol. 13, issue 1, pp. 73-79, 2017 01 15. PMCID: PMC5181618  PMID: 27655454
Toosizadeh, N., C. Berry, C. Bime, B. Najafi, M. Kraft, and J. Mohler, "Assessing upper-extremity motion: An innovative method to quantify functional capacity in patients with chronic obstructive pulmonary disease.", PLoS One, vol. 12, issue 2, pp. e0172766, 2017. PMCID: PMC5325547  PMID: 28235045
Day, S. E., L. A. Garcia, R. L. Coletta, L. E. Campbell, T. R. Benjamin, E. A. De Filippis, J. A. Madura, L. J. Mandarino, L. R. Roust, and D. K. Coletta, "Alterations of sorbin and SH3 domain containing 3 (SORBS3) in human skeletal muscle following Roux-en-Y gastric bypass surgery.", Clin Epigenetics, vol. 9, pp. 96, 2017. PMCID: PMC5581422  PMID: 28883895
Ganley, K. J., P. R. Bosch, J. E. Blair, F. Rischard, and J. N. Galgiani, "Oxygen Consumption Deficits in Patients With Residual Fatigue After Primary Coccidioidomycosis", Open Forum Infectious Diseases, vol. 4, issue 3, 06/2017.


Galgiani, J. N., N. M. Ampel, J. E. Blair, A. Catanzaro, F. Geertsma, S. E. Hoover, R. H. Johnson, S. Kusne, J. Lisse, J. D. MacDonald, et al., "Executive Summary: 2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis.", Clin Infect Dis, vol. 63, issue 6, pp. 717-22, 2016 Sep 15. PMID: 27559032