The following published papers illustrate the latest investigative endeavors of faculty and research staff in the University of Arizona Department of Medicine and its 14 divisions. Click the PubMed links to read on about how they're setting the pace for the future of health care and precision medicine solutions to improve patient lives in Arizona and beyond.


Buck, D. W., and K. L. Herbst, "Lipedema: A Relatively Common Disease with Extremely Common Misconceptions.", Plast Reconstr Surg Glob Open, vol. 4, issue 9, pp. e1043, 2016 Sep. PMCID: PMC5055019  PMID: 27757353
Reynolds, S., M. Shaheen, G. Olson, M. Barry, J. Wu, and T. Bocklage, "A Case of Primary Mammary Analog Secretory Carcinoma (MASC) of the Thyroid Masquerading as Papillary Thyroid Carcinoma: Potentially More than a One Off.", Head Neck Pathol, vol. 10, issue 3, pp. 405-13, 2016 Sep. PMCID: PMC4972767  PMID: 27075025
Wang, L., Z. Gao, L. Wang, and Y. Gao, "Upregulation of nuclear factor-κB activity mediates CYP24 expression and reactive oxygen species production in indoxyl sulfate-induced chronic kidney disease.", Nephrology (Carlton), vol. 21, issue 9, pp. 774-81, 2016 Sep. PMID: 26567049
Albergotti, W. G., K. S. Davis, S. Abberbock, J. E. Bauman, J. Ohr, D. A. Clump, D. E. Heron, U. Duvvuri, S. Kim, J. T. Johnson, et al., "Association of pretreatment body mass index and survival in human papillomavirus positive oropharyngeal squamous cell carcinoma.", Oral Oncol, vol. 60, pp. 55-60, 2016 Sep. PMCID: PMC4991628  PMID: 27531873
Chiosea, S. I., L. D. R. Thompson, I. Weinreb, J. E. Bauman, A. M. Mahaffey, C. Miller, R. L. Ferris, and W. E. Gooding, "Subsets of salivary duct carcinoma defined by morphologic evidence of pleomorphic adenoma, PLAG1 or HMGA2 rearrangements, and common genetic alterations.", Cancer, vol. 122, issue 20, pp. 3136-3144, 2016 Oct 15. PMCID: PMC5048512  PMID: 27379604
Liu, Z., B. D. Gray, C. Barber, M. Bernas, M. Cai, L. R. Furenlid, A. Rouse, C. Patel, B. Banerjee, R. Liang, et al., "Characterization of TCP-1 probes for molecular imaging of colon cancer.", J Control Release, vol. 239, pp. 223-30, 2016 Oct 10. PMCID: PMC5037054  PMID: 27574992
Boehme, J., X. Sun, K. V. Tormos, W. Gong, M. Kellner, S. A. Datar, R. Johnson Kameny, J. X. - J. Yuan, G. W. Raff, J. R. Fineman, et al., "Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation.", Am J Physiol Heart Circ Physiol, vol. 311, issue 4, pp. H944-H957, 2016 Oct 01. PMCID: PMC5114466  PMID: 27591215
Noble, J. A., R. G. Nelson, G. D. Fufaa, P. Kang, S. Chani Shafir, and J. N. Galgiani, "Effect of Geography on the Analysis of Coccidioidomycosis-Associated Deaths, United States.", Emerg Infect Dis, vol. 22, issue 10, pp. 1821-3, 2016 Oct. PMCID: PMC5038404  PMID: 27649029
Miles, B., S. M. Miller, J. M. Folkvord, D. N. Levy, E. G. Rakasz, P. J. Skinner, and E. Connick, "Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.", PLoS Pathog, vol. 12, issue 10, pp. e1005924, 2016 Oct. PMCID: PMC5055335  PMID: 27716848
Muser, D., P. Santangeli, S. A. Castro, R. K. Pathak, J. J. Liang, T. Hayashi, S. Magnani, F. C. Garcia, M. D. Hutchinson, G. G. Supple, et al., "Long-Term Outcome After Catheter Ablation of Ventricular Tachycardia in Patients With Nonischemic Dilated Cardiomyopathy.", Circ Arrhythm Electrophysiol, vol. 9, issue 10, 2016 Oct. PMID: 27733494
Narra, H. P., L. F. Shubitz, A. M Mandel, H. T. Trinh, K. Griffin, A. S. Buntzman, J. A. Frelinger, J. N. Galgiani, and M. J. Orbach, "A Coccidioides posadasii CPS1 Deletion Mutant Is Avirulent and Protects Mice from Lethal Infection.", Infect Immun, vol. 84, issue 10, pp. 3007-16, 2016 Oct. PMCID: PMC5038059  PMID: 27481239
Morel, B., P. Franck, J. Bidange, S. Sergeyev, D. Smith, J. Moseley, and B. Uw Maes, "Concise Xanthine Synthesis via a Double Amidination Reaction of a 6-Chlorouracil with Amidines using Base Metal Catalysis.", ChemSusChem, 2016 Nov 29. PMID: 27899009
Durack, J., S. V. Lynch, S. Nariya, N. R. Bhakta, A. Beigelman, M. Castro, A-M. Dyer, E. Israel, M. Kraft, R. J. Martin, et al., "Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment.", J Allergy Clin Immunol, 2016 Nov 10. PMID: 27838347
Sadek, M. M., S. Maeda, W. Chik, P. Santangeli, E. S. Zado, R. D. Schaller, G. E. Supple, D. S. Frankel, M. D. Hutchinson, F. C. Garcia, et al., "Recurrent atrial arrhythmias in the setting of chronic pulmonary vein isolation.", Heart Rhythm, vol. 13, issue 11, pp. 2174-2180, 2016 Nov. PMID: 27544746
F Hodi, S., J. Chesney, A. C. Pavlick, C. Robert, K. F. Grossmann, D. F. McDermott, G. P. Linette, N. Meyer, J. K. Giguere, S. S. Agarwala, et al., "Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial.", Lancet Oncol, vol. 17, issue 11, pp. 1558-1568, 2016 Nov. PMID: 27622997
Liang, J. J., M. A. Elafros, D. Muser, R. K. Pathak, P. Santangeli, E. S. Zado, D. S. Frankel, G. E. Supple, R. D. Schaller, R. Deo, et al., "Pulmonary Vein Antral Isolation and Nonpulmonary Vein Trigger Ablation Are Sufficient to Achieve Favorable Long-Term Outcomes Including Transformation to Paroxysmal Arrhythmias in Patients With Persistent and Long-Standing Persistent Atrial Fibrillation.", Circ Arrhythm Electrophysiol, vol. 9, issue 11, 2016 Nov. PMID: 27784738
Tey, K. Rou, T. Kemmerly, and B. Banerjee, "NSAID-induced pyloric stenosis leading to oesophageal intramucosal dissection.", BMJ Case Rep, vol. 2016, 2016 May 19. PMID: 27199442
Geiger, J. L., J. R. Grandis, and J. E. Bauman, "The STAT3 pathway as a therapeutic target in head and neck cancer: Barriers and innovations.", Oral Oncol, vol. 56, pp. 84-92, 2016 May. PMID: 26733183
Denlinger, L. C., T. S. King, J. Carlos Cardet, T. Craig, F. Holguin, D. J. Jackson, M. Kraft, S. P. Peters, K. Ross, K. Sumino, et al., "Vitamin D Supplementation and the Risk of Colds in Patients with Asthma.", Am J Respir Crit Care Med, vol. 193, issue 6, pp. 634-41, 2016 Mar 15. PMCID: PMC4824938  PMID: 26540136
Kohler, S. L., M. N. Pham, J. M. Folkvord, T. Arends, S. M. Miller, B. Miles, A. L. Meditz, M. McCarter, D. N. Levy, and E. Connick, "Germinal Center T Follicular Helper Cells Are Highly Permissive to HIV-1 and Alter Their Phenotype during Virus Replication.", J Immunol, vol. 196, issue 6, pp. 2711-22, 2016 Mar 15. PMCID: PMC4779697  PMID: 26873986
Ledford, J. G., K. J. Addison, D. Francisco, M. W. Foster, D. R. Voelker, L. G. Que, and M. Kraft, "Genetic Variation in Surfactant Protein-A2 Results in Altered Regulation of Eosinophil Activities and Enhanced Eosinophilia in Patients with Asthma.", Ann Am Thorac Soc, vol. 13 Suppl 1, pp. S101, 2016 Mar. PMCID: PMC5015737  PMID: 27027938
Hecker, L., and V. J. Thannickal, "Getting to the core of fibrosis: targeting redox imbalance in aging.", Ann Transl Med, vol. 4, issue 5, pp. 93, 2016 Mar. PMCID: PMC4791330  PMID: 27047952
A Schissler, G., Q. Li, J. L. Chen, C. Kenost, I. Achour, D. D Billheimer, H. Li, W. W. Piegorsch, and Y. A. Lussier, "Analysis of aggregated cell-cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells.", Bioinformatics, vol. 32, issue 12, pp. i80-i89, 2016 Jun 15. PMCID: PMC4908332  PMID: 27307648
Wang, T., B. Mathew, X. Wu, Y. Shimizu, A. N. Rizzo, S. M. Dudek, R. R. Weichselbaum, J. R. Jacobson, L. Hecker, and J. G. N. Garcia, "Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury.", Pulm Circ, vol. 6, issue 2, pp. 234-9, 2016 Jun. PMCID: PMC4869928  PMID: 27252850
Bime, C., T. Zhou, T. Wang, M. J. Slepian, J. G. N. Garcia, and L. Hecker, "Reactive oxygen species-associated molecular signature predicts survival in patients with sepsis.", Pulm Circ, vol. 6, issue 2, pp. 196-201, 2016 Jun. PMCID: PMC4869924  PMID: 27252846
Zhou, X., R. Li, X. Liu, L. Wang, P. Hui, L. Chan, P. K. Saha, and Z. Hu, "ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity.", Sci Rep, vol. 6, pp. 29669, 2016 Jul 14. PMCID: PMC4944137  PMID: 27411515
Indik, J. H., "True or False: Prognosis Is Excellent for Sudden Cardiac Death Survivors Due to Variant Angina.", J Am Coll Cardiol, vol. 68, issue 2, pp. 146-8, 2016 Jul 12. PMID: 27386767
Ling, D. C., J. A. Vargo, R. L. Ferris, J. Ohr, D. A. Clump, W-Y. Wendy Yau, U. Duvvuri, S. Kim, J. T. Johnson, J. E. Bauman, et al., "Risk of Severe Toxicity According to Site of Recurrence in Patients Treated With Stereotactic Body Radiation Therapy for Recurrent Head and Neck Cancer.", Int J Radiat Oncol Biol Phys, vol. 95, issue 3, pp. 973-80, 2016 Jul 01. PMID: 27302512
Harpel, K., R. Dawson Baker, B. Amirsolaimani, S. Mehravar, J. Vagner, T. O. Matsunaga, B. Banerjee, and K. Kieu, "Imaging of targeted lipid microbubbles to detect cancer cells using third harmonic generation microscopy.", Biomed Opt Express, vol. 7, issue 7, pp. 2849-60, 2016 Jul 01. PMCID: PMC4948635  PMID: 27446711
Petukhova, T. A., N. Foolad, N. Prakash, V. Y. Shi, V. R. Sharon, L. O'Brecht, I. A. Ali, S. Feldstein, J. Halls, Q. Wang, et al., "Objective volumetric grading of postacne scarring.", J Am Acad Dermatol, vol. 75, issue 1, pp. 229-31, 2016 Jul. PMID: 27317527
Banerjee, B., N. J. Shaheen, J. A. Martinez, C-H. Hsu, E. Trowers, B. A. Gibson, G. Della'Zanna, E. Richmond, and H-H. Sherry Chow, "Clinical Study of Ursodeoxycholic Acid in Barrett's Esophagus Patients.", Cancer Prev Res (Phila), vol. 9, issue 7, pp. 528-33, 2016 Jul. PMCID: PMC4930711  PMID: 26908564
Bauman, J. E., Y. Zang, M. Sen, C. Li, L. Wang, P. A. Egner, J. W. Fahey, D. P. Normolle, J. R. Grandis, T. W. Kensler, et al., "Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane.", Cancer Prev Res (Phila), vol. 9, issue 7, pp. 547-57, 2016 Jul. PMCID: PMC4930727  PMID: 27339168
Grief, S. N., J. Patel, K. M. Kochendorfer, L. A. Green, Y. A. Lussier, J. Li, M. Burton, and A. D. Boyd, "Simulation of ICD-9 to ICD-10-CM Transition for Family Medicine: Simple or Convoluted?", J Am Board Fam Med, vol. 29, issue 1, pp. 29-36, 2016 Jan-Feb. PMID: 26769875
Montoya-Durango, D. E., K. A. Ramos, P. Bojang, L. Ruiz, I. N. Ramos, and K. S. Ramos, "LINE-1 silencing by retinoblastoma proteins is effected through the nucleosomal and remodeling deacetylase multiprotein complex.", BMC Cancer, vol. 16, pp. 38, 2016 Jan 25. PMCID: PMC4727354  PMID: 26810492
Wilken, R., M. A. Fung, V. Y. Shi, M. Y. Cheng, F. Patel, H. Sultani, and E. Maverakis, "Cyclosporine-induced sebaceous hyperplasia in a hematopoetic stem cell transplant patient: delayed onset of a common adverse event.", Dermatol Online J, vol. 22, issue 1, 2016 Jan 15. PMID: 26990469
Mehravar, S., B. Banerjee, H. Chatrath, B. Amirsolaimani, K. Patel, C. Patel, R. A. Norwood, N. Peyghambarian, and K. Kieu, "Label-free multi-photon imaging of dysplasia in Barrett's esophagus.", Biomed Opt Express, vol. 7, issue 1, pp. 148-57, 2016 Jan 01. PMCID: PMC4722899  PMID: 26819824
Qiao, Y-F., W-J. Guo, L. Li, S. Shao, X. Qiao, J-J. Shao, Q. Zhang, R-S. Li, and L-H. Wang, "Melatonin attenuates hypertension-induced renal injury partially through inhibiting oxidative stress in rats.", Mol Med Rep, vol. 13, issue 1, pp. 21-6, 2016 Jan. PMCID: PMC4686099  PMID: 26531807
Ingram, J. L., D. Slade, T. D. Church, D. Francisco, K. Heck, W. R Sigmon, M. Ghio, A. Murillo, R. Firszt, N. L. Lugogo, et al., "Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13-Suppressed Elastin in Airway Fibroblasts in Asthma.", Am J Respir Cell Mol Biol, vol. 54, issue 1, pp. 41-50, 2016 Jan. PMCID: PMC4742923  PMID: 26074138
Yu, Y-R. A., D. F. Hotten, Y. Malakhau, E. Volker, A. J. Ghio, P. W. Noble, M. Kraft, J. W. Hollingsworth, M. D. Gunn, and R. M. Tighe, "Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues.", Am J Respir Cell Mol Biol, vol. 54, issue 1, pp. 13-24, 2016 Jan. PMCID: PMC4742930  PMID: 26267148
Iii, H. L. Twigg, K. S. Knox, J. Zhou, K. A. Crothers, D. E. Nelson, E. Toh, R. B. Day, H. Lin, X. Gao, Q. Dong, et al., "Effect of Advanced HIV Infection on the Respiratory Microbiome.", Am J Respir Crit Care Med, 2016 Feb 2. PMID: 26835554
Pouladi, N., C. Bime, J. G. N. Garcia, and Y. A. Lussier, "Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing.", Transl Res, vol. 168, pp. 22-39, 2016 Feb. PMCID: PMC4658294  PMID: 26006746
Nyenhuis, S. M., J. A. Krishnan, A. Berry, W. J. Calhoun, V. M. Chinchilli, L. Engle, N. Grossman, F. Holguin, E. Israel, R. A. Kittles, et al., "Race is associated with differences in airway inflammation in patients with asthma.", J Allergy Clin Immunol, 2016 Dec 31. PMID: 28069248
Marur, S., S. Li, A. J. Cmelak, M. L. Gillison, W. J. Zhao, R. L. Ferris, W. H. Westra, J. Gilbert, J. E. Bauman, L. I. Wagner, et al., "E1308: Phase II Trial of Induction Chemotherapy Followed by Reduced-Dose Radiation and Weekly Cetuximab in Patients With HPV-Associated Resectable Squamous Cell Carcinoma of the Oropharynx- ECOG-ACRIN Cancer Research Group.", J Clin Oncol, pp. JCO2016683300, 2016 Dec 28. PMID: 28029303
Chen, T., Q. Zhou, H. Tang, M. Bozkanat, J. X. - J. Yuan, U. J Raj, and G. Zhou, "miR-17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia-Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation.", J Am Heart Assoc, vol. 5, issue 12, 2016 Dec 05. PMCID: PMC5210422  PMID: 27919930
Geiger, J. L., J. E. Bauman, M. K. Gibson, W. E. Gooding, P. Varadarajan, A. Kotsakis, D. Martin, J. Silvio Gutkind, M. L. Hedberg, J. R. Grandis, et al., "Phase II trial of everolimus in patients with previously treated recurrent or metastatic head and neck squamous cell carcinoma.", Head Neck, vol. 38, issue 12, pp. 1759-1764, 2016 Dec. PMID: 27232378
Wang, L., Z. Gao, L. Wang, and Y. Gao, "Loss of miR-125b contributes to upregulation of CYP24 in uraemic rats.", Nephrology (Carlton), vol. 21, issue 12, pp. 1063-1068, 2016 Dec. PMID: 26729468
Tang, H., A. A. Desai, and J. X. - J. Yuan, "Genetic Insights into Pulmonary Arterial Hypertension. Application of Whole-Exome Sequencing to the Study of Pathogenic Mechanisms.", Am J Respir Crit Care Med, vol. 194, issue 4, pp. 393-7, 2016 Aug 15. PMCID: PMC5003333  PMID: 27525458
Stein, M. M., C. L. Hrusch, J. Gozdz, C. Igartua, V. Pivniouk, S. E. Murray, J. G. Ledford, M. Marques do Santos, R. L. Anderson, N. Metwali, et al., "Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.", N Engl J Med, vol. 375, issue 5, pp. 411-21, 2016 Aug 04. PMCID: PMC5137793  PMID: 27518660
Carr, T. F., and M. Kraft, "Chronic Infection and Severe Asthma.", Immunol Allergy Clin North Am, vol. 36, issue 3, pp. 483-502, 2016 Aug. PMID: 27401621
Pulko, V., J. S. Davies, C. Martinez, M. C. Lanteri, M. P. Busch, M. S. Diamond, K. Knox, E. C. Bush, P. A. Sims, S. Sinari, et al., "Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses.", Nat Immunol, vol. 17, issue 8, pp. 966-75, 2016 Aug. PMCID: PMC4955715  PMID: 27270402